Publications

Scientific

publications

Presentations

PR
materials

Project
results

Scientific

publications

Presentations

PR
materials

Project
results

Scientific publications

 

  • POSTER: ‘A two-stage prediction model for heterogeneous effects for many treatment options’ – Konstantina Chalkou (University of Bern) Graduate School for Health Sciences Symposium 2019, Parkhotel Gunten, Thun Switzerland  November 19 – 20, 2019 DOWNLOAD

 

  • POSTER: ‘Flexible Generic Framework for Evidence Synthesis in Health Technology Assessment’ – Tasnim Hamza (University of Bern) Graduate School for Health Sciences Symposium 2019, Parkhotel Gunten, Thun Switzerland  November 19 – 20, 2019 DOWNLOAD

 

  • POSTER (in Spanish): HTx: ‘Marco para la próxima generación de Evaluación de Tecnologías Sanitarias en Europa’ – M. Elena Hernando, Gema García-Sáez (Universidad Politécnica de Madrid), Annual Conference of the Biomedical Enginnering Spanish Society (CASEIB2019) 27-29 November 2019, Santander, Spain DOWNLOAD

 

  • POSTER: ‘NEXT GENERATION HEALTH TECHNOLOGY ASSESSMENT TO SUPPORT PATIENT-CENTRED, SOCIETALLY ORIENTED, REAL-TIME DECISION-MAKING IN DIABETES: CLINICAL DECISION SUPPORT SYSTEMS/ADVISORS’ – G. Garcia-Sanchez (Universidad Politécnica de Madrid) International Conference on Advanced Technologies & Treatments for Diabetes, Madrid, 2020 DOWNLOAD

 

  • POSTER: ‘A two-stage prediction model for heterogeneous effects for many treatment options’ – Konstantina Chalkou (University of Bern) Swiss Public Health Conference 2020 in Lucern, 2-4 September 2020 DOWNLOAD

 

  • POSTER: ‘Challenges in Health Technology Assessment of Complex Health Technologies’ – Milou A. Hogervorst, Rick A. Vreman, Aukje K. Mantel-Teeuwisse, Wim G.Goettsch (Utrecht University & The Netherlands National Health Care Institute (ZIN)) Virtual ISPOR Europe 2020, 16 – 19 November 2020 DOWNLOAD

 

  • POSTER: ‘The Use Of The Sandbox Approach In The Context of HTA: A Literature Review’ – Leckenby, E., Dawoud, D., Jonsson, P. (NICE) Virtual ISPOR Europe 2020, 16 – 19 November 2020 DOWNLOAD

 

  • ARTICLE: Chalkou, K., Steyerberg, E., Egger, M., Manca, A., Pellegrini, F., Salanti, G. (2020). A two-stage prediction model for heterogeneous effects of many treatment options: application to drugs for Multiple Sclerosis. DOWNLOAD

 

  • ARTICLE: Ofori-Asenso, R., Hallgreen, C. E., De Bruin, M. L. (2020). Improving Interactions Between Health Technology Assessment Bodies and Regulatory Agencies: A Systematic Review and Cross-Sectional Survey on Processes, Progress, Outcomes, and Challenges. Frontiers in Medicine. DOWNLOAD

 

  • ARTICLE: Hamza, T., Cipriani, A., Furukawa, T. A., Egger, M., Orsini, N., Salanti, G. (2021). A Bayesian dose-response meta-analysis model: A simulations study and application. Statistical Methods in Medical Research. DOWNLOAD

 

  • ARTICLE: Leeuwenberg, A. M., van Smeden, M., Langendijk, J. A.,  van der Schaaf, A., Mauer, M. E., Moons, K. G. M., Reitsma, J. B., Schuit, E. (2021). Comparing methods addressing multi-collinearity when developing prediction models. DOWNLOAD

 

  • ARTICLE: Chalkou, K., Steyerberg, E., Egger, M., Manca, A., Pellegrini, F., Salanti, G. (2021). A Two-Stage Prediction Model For Heterogeneous Effects of Treatments. Statistics in Medicin. DOWNLOAD

 

  • ARTICLE: Stoicescu, O., Ferreira, E., Tamminen, S., Siirtola, P., Chandra, G., Veijola, R., Röning, J. (2021). ClinFlow – An Interactive Application for Clinical Data Mining. Public Health and Informatics. DOWNLOAD

 

  • POSTER: ‘Data-driven Subgroups Of Patients With Type 1 Diabetes Based On Health Technology For Insulin Delivery’ – Somolinos-Simón, F.J., García-Sáez, G., Tapia-Galisteo , J., M.E. Hernando, M. E. (Universidad Politécnica de Madrid) HTAi 2021 Virtual Annual Meeting, 19-23 June 2021 DOWNLOAD

 

  • ARTICLE: Leckenby, E., Dawoud, D., Bouvy, J., Páll, J. (2021). The Sandbox Approach and its Potential for Use in Health Technology Assessment: A Literature Review. Applied Health Economics & Health Policy. DOWNLOAD

 

  • ARTICLE: Chalkou, K., Steyerberg, E., Bossuyt, P., Subramanian, S., Benkert, P., Kuhle, J., Disanto, G., Kappos, L., Egger, M., Salanti, G. (2021). Development, validation and clinical usefulness of a prognostic model for relapse in relapsing-remitting multiple sclerosis. DOWNLOAD 

Presentations

 

A two-stage prediction model for heterogeneous effects for many treatment options’ Konstantina Chalkou (University of Bern, Switzerland) XXXIst Conference of the Austro-Swiss Region [ ROeS ] of the International Biometric Society (Lausanne, Switzerland, September 9-12, 2019) DOWNLOAD

 

A Bayesian two-stage dose-response meta-analysis model’ Tasnim Hamza (University of Bern, Switzerland) XXXIst Conference of the Austro-Swiss Region [ ROeS ] of the International Biometric Society (Lausanne, Switzerland, September 9-12, 2019) DOWNLOAD

 

The need for better HTA methodology for more complex and personalised medicine’ Wim Goettsch, (Utrecht University, The Netherlands) Pharmaceutical Pricing and Reimbursement (PPRI) Conference (Vienna, Austria October 23-24, 2019) DOWNLOAD

 

A two-stage prediction model for heterogeneous effects of many treatment options: application to drugs for Multiple Sclerosis’ Konstantina Chalkou, Georgia Salanti (University of Bern, Switzerland),  2nd HTx General Assembly  (Bern, Switzerland 6-7 February 2020) DOWNLOAD

 

‘Improving synergy between HTA bodies and regulatory agencies’ Richard Ofori-Asenso (University of Copenhagen, Denmark) Internal UCPH, Copenhagen Centre for Regulatory Science Scientific Advisory Board meeting (online event June 18, 2020) DOWNLOAD

 

‘HTx Next Generation Health Technology Assessment EU Horizon 2020 Project’ Dr Dalia Dawoud, (NICE, United Kingdom) GINAHTA webinarHTA & Guidelines: What can we learn from each other? (online event June 29 2020) DOWNLOAD

 

‘A prediction model of heterogeneous treatment effects using randomized and observational data’, Konstantina Chalkou (University of Bern, Switzerland), 41st Annual Conference of the International Society for Clinical Biostatistics (Krakow, Poland 23-27 August 2020) DOWNLOAD

 

‘Bayesian dose-response network meta-analysis’, Tasnim Hamza (University of Bern, Switzerland), 41st Annual Conference of the International Society for Clinical Biostatistics (Krakow, Poland 23-27 August 2020) DOWNLOAD

 

‘Incorporating single-arm observational evidence in network meta-analysis: an assessment of the available methods’, Tasnim Hamza (University of Bern, Switzerland), Swiss Public Health Conference (online event 2 – 3 September 2020) DOWNLOAD

 

‘HTx webinar Case Study 1 – Proton Therapy among head and neck cancer patients’ Enricol Clementel/Marjan Sharabiani, Prof. J.A.Langendijk, Dr. A.M.Leeuwenberg/Dr. Ewout Schuit, Dr. Lifang Liu, EURORDIS (online webinar organised by EORTC November 11 2020) VIDEO

 

‘A prediction model of heterogeneous treatment effects using randomized and observational data’ Konstantina Chalkou (University of Bern, Switzerland), Virtual ISPOR 2020 (online event 16-19 November 2020) DOWNLOAD

 

‘Flexible generic framework for evidence synthesis in health technology assessment’ Tasnim Hamza (University of Bern, Switzerland), Virtual ISPOR 2020 (online event 16-19 November 2020) DOWNLOAD

 

‘The Future of Health Technology Assessment’ Dr Dalia Dawoud, (NICE, United Kingdom) 2nd Annual Conference of the BMC Journal of Pharmaceutical Policy and Practice (online event November 21 2020) DOWNLOAD

 

‘Collinearity in Prognostic Models for Dysphagia’ Artuur Leeuwenberg, PhD (University Medical Center Utrecht, The Netherlands) MEMTAB 2020 Virtual Symposium (online event 10-11 December 2020) DOWNLOAD and VIDEO

 

‘Flexible generic framework for evidence synthesis in health technology assessment’ Tasnim Hamza (University of Bern, Switzerland) 3rd HTx Consortium Meeting (online event 24-25 March 2021) DOWNLOAD

 

‘A two-stage model for individualized predictions under several treatment options for RRMS’ Konstantina Chalkou, Georgia Salanti (University of Bern, Switzerland), 3rd HTx Consortium Meeting (online event 24-25 March 2021) DOWNLOAD

 

‘Dwarsverband Bevorderen Kwaliteit’ (in Dutch) Dr. Elise Quik (Zorginstituut Nederland, The Netherlands) Internal meeting at Zorginstituut Nederland (online event 19 April 2021) DOWNLOAD

 

‘Synergies between regulatory authorities, HTA organisations and clinical guideline developers’ Wim Goettsch and Milou Hogervorst (with additional moderators, prof. Aukje Mantel-Teeuwisse, prof. Bert Leufkens, prof. Marieke de Bruin, dr. Rick Vreman, dr. Junfeng Wang, dr. Mathias Mollebeak) (Utrecht University, The Netherlands) Deliverable 4.3 Workshop on synergies (Focus Groups) (online event 10 May 2021) DOWNLOAD

 

‘Data Synthesis for precision medicine models’ Gunjan Chandra (University of Oulu, Finland) DELTA Workshop (online event 8 June 2021) DOWNLOAD

 

‘crosnma: To synthesize cross-design evidence and cross-format data using network meta-analysis’ Tasnim Hamza (University of Bern, Switzerland) Workshop on crosnma (online event 15 June 2021) DOWNLOAD and VIDEO

 

‘Decision curve analysis for personalized treatment choice between multiple options’ Konstantina Chalkou (University of Bern, Switzerland), 42nd (Virtual) Annual Conference of the International Society for Clinical Biostatistics (ISCB) (online event 18-22 July 2021) DOWNLOAD

 

‘Flexible generic framework for evidence synthesis in health technology assessment using network meta-analysis’ Tasnim Hamza (University of Bern, Switzerland), 42nd (Virtual) Annual Conference of the International Society for Clinical Biostatistics (ISCB) (online event 18-22 July 2021) DOWNLOAD

 

‘A prediction model of heterogeneous treatment effects using randomized and observational data’ Konstantina Chalkou (University of Bern, Switzerland), Webinar Case Study 3 HTx (online event 20-21 October 2021) DOWNLOAD

PR materials

 

HTx Introductory slide deck  DOWNLOAD

 

HTx introductory video (shorter version for the general public) VIDEO

 

HTx introductory video (longer version for patients with subtitles in 5 languages) VIDEO

 

HTx Newsletter September 2019 DOWNLOAD

 

HTx Newsletter April 2020 DOWNLOAD

 

HTx Newsletter March 2021 DOWNLOAD

 

HTx Newsletter July 2021 DOWNLOAD

Project results

 

HTx Expert Forum meeting November 25, 2019 Barcelona (Spain) – Summary poster of results DOWNLOAD

HTx Deliverable 1.1: Systematic review on how (cost-) effectiveness of combinations of health technologies, individualised/personalised treatments and treatment pathways is currently being assessed by HTA bodies DOWNLOAD

HTx Deliverable 1.3: Review on treatment modalities for patient with myelodysplastic syndrome (MDS) DOWNLOAD

HTx Deliverable 1.4: Report describing the available data sources in relapsing-remitting Multiple Sclerosis case study 3 DOWNLOAD

HTx Deliverable 1.5: Report on the relevant treatment combinations for the T1DM and T2DM patients DOWNLOAD

HTx Deliverable 4.4: Overview of the development of the use of RWD including a review of national consensus methods currently developed DOWNLOAD

HTx Deliverable 4.5: Review on suitable payment models for co-dependent technologies, combination technologies and advanced therapy medicinal products (ATMP’s) DOWNLOAD

HTx Project Result: PROM Toolbox DOWNLOAD

HTx Project Result: PROM-Guide DOWNLOAD

HTx Project Result: The Literature Review on the Use of PROMs Toolbox DOWNLOAD

HTx Project Result: PROM-Cycle DOWNLOAD

HTx Project Result: The Linnean Menu DOWNLOAD

HTx Expert Forum 2021 meeting presentations (3rd June 2021) DOWNLOAD