Imagine an individual patient who visits the doctor for a medical problem. The doctor knows this patient’s clinical history (including her use of different health technologies, such as medical devices, e-health technologies and drugs), her preferences and health outcomes.

Adequate clinical studies and real-world data analysis have resulted in a real-time decision support system that the doctor and the patient can use to obtain person-centered information (in a user-friendly format) about risks, benefits, outcomes and costs associated with a range of possible strategies to manage the patient’s ailment.

The same information is made available to HTA agencies whose decisions are informed by means of this information, analysed at the level of individuals and summarised at the subgroup and population level for the benefit of payers’ decision-making. This framework is what we envision as HTx.